It is feasible that the TCAB1-mediated “swap” isn't captured with the conformation characterized from the cryo-EM structure. Characterizing a higher fraction from the holoenzyme particles within the active chromatographic portion will likely result in the identification of additional conformational states. The cryo-EM characterization of human telomerase also reveals the presence https://andrewa566xhq7.jasperwiki.com/user