Inhibition of the synthesis of an essential ribosomal protein (r-protein) abrogates the assembly of its cognate subunit. while assembly of the other subunit continues. Ribosomal components that are not stably incorporated into ribosomal particles due to the disrupted assembly are rapidly degraded. The 60S protein uL18/L5 is an exception and this protein accumulates extra-ribosomally d... https://www.knowall.blog/