Poor/In depth Metabolizers, CYP2D6 The formation from the Lively metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Roughly 7% on the population has decreased action on the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme method. These people today are “poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, among other https://gracel986dxo6.wikifordummies.com/user