Where a lone pair from the nucleophile overlaps with the sigma* orbital in the leaving group. Even so, this action does not provide the very same sensitivity to steric hindrance given that the SN2 reaction, as we are going to see. Having said that, the proof relating to their efficacy https://bromazolamliquidsolution17394.ezblogz.com/69112925/is-bromazolam-an-opioid-an-overview